Jul 17, 2014

Mechanism of action of thalidomide elucidated

Scientists led by Nicolas Thomä have clarified the workings of thalidomide at the molecular level. Their analysis of various structures, published in Nature, indicates that the drug can interfere with cellular processes in two different ways - once preventing and once promoting protein degradation - thus explaining its diverse clinical effects. Read more

Jul 04, 2014

Inducing visual function

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Jun 19, 2014

Interfering with breast cancer metastasis

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Jun 10, 2014

FMI scientists shed light on how microRNAs repress protein synthesis

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Next seminars & events

Aug 18, 2014. Time: 16.00  FMI Room 530  Add to my calendar  Register for this event

Signatures of mutational processes in human cancer
Michael Stratton, Wellcome Trust Sanger Institute, Hinxton, UK
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Aug 26, 2014. Time: 12.15  FMI Room 530  Add to my calendar  Register for this event

Circulating tumor cells: Detection, biology and clinical implications
Klaus Pantel, University Medical Center, Hamburg-Eppendorf, Germany

Aug 28, 2014. Time: 11.30  FMI Room 530  Add to my calendar  Register for this event

Title t.b.a.
Anthony Leonardo, Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA, USA

Aug 29, 2014. Time: 14.00  FMI Room 530  Add to my calendar  Register for this event

From static structures to molecular movies: pushing the boundaries of X-ray crystallography
Wei Yang, National Institute of Health, Bethesda, MD, USA

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Recent Publications

Busskamp V, Krol J, Nelidova D, Daum J, Szikra T, Tsuda B, Jüttner J, Farrow K, Gross Scherf B, Patino Alvarez CP, Genoud C, Sothilingam V, Tanimoto N, Stadler M, Seeliger M, Stoffel M, Filipowicz W, Roska B miRNAs 182 and 183 Are Necessary to Maintain Adult Cone Photoreceptor Outer Segments and Visual Function Neuron. 2014 Jul; [Epub ahead of print]

Weisman R, Cohen A, Gasser SM TORC2-a new player in genome stability EMBO Mol Med. 2014 Jul; [Epub ahead of print]

Sausgruber N, Coissieux MM, Britschgi A, Wyckoff J, Aceto N, Leroy C, Stadler MB, Voshol H, Bonenfant D, Bentires-Alj M Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases Oncogene. 2014 Jun; [Epub ahead of print]

Duss S, Brinkhaus H, Britschgi A, Cabuy E, Frey DM, Schaefer DJ, Bentires-Alj M Mesenchymal precursor cells maintain the differentiation and proliferation potentials of breast epithelial cells Breast Cancer Res. 2014 Jun; 16 (3):R60

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