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Jan 19, 2010

Dicer shuttles to nucleus and accumulates to form heterochromatin

Scientists from the Friedrich Miescher Institute for Biomedical Research of the Novartis Research Foundation have solved a yeast Dicer riddle. In a publication in Developmental Cell, they demonstrate the nuclear localization of Dicer in fission yeast, thereby linking an important Dicer function to its site of action. They further elucidated a novel cytoplasm-nucleus shuttling process for Dicer that may also be relevant for other organisms. Read more

Jan 18, 2010

Silvia Arber receives prestigious ERC research grant

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Nov 03, 2009

Botond Roska selected 2009 EMBO Young Investigator

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Oct 20, 2009

Dirk Schübeler, a newly elected EMBO member

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Next seminars & events

Feb 16, 2010. Time: 12.15  FMI Room 530  Add to my calendar  Register for this event

New insights in normal and cancer stem cell biology
Giuseppina Bonizzi, IFOM-IEO Campus, Milan, Italy

Feb 17, 2010. Time: 16.00  FMI Room 530  Add to my calendar  Register for this event

Mammalian synthetic biology - from tools to therapies
Martin Fussenegger, ETH Zürich, D-BSSE, Basel

Feb 24, 2010. Time: 14.00  FMI Room 539  Add to my calendar  Register for this event

Repeated functional imaging of mouse barrel cortex using a genetically encoded calcium indicator
David Margolis, Brain Research Institute, University of Zürich, Switzerland

Feb 25, 2010. Time: 16.00  FMI Room 530  Add to my calendar  Register for this event

Oocyte-to-zygote transition in the mouse: the miRNA paradox
Petr Svoboda, Institute of Molecular Genetics, Videnska, Czech Republic

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Recent Publications

Emmerth S, Schober H, Gaidatzis D, Roloff T, Jacobeit K, Bühler M Nuclear Retention of Fission Yeast Dicer Is a Prerequisite for RNAi-Mediated Heterochromatin Assembly Dev Cell. 2010 Jan;18:102-113
Bühler, M.

Tiwari VK, Baylin SB Mapping networks of protein-mediated physical interactions between chromatin elements Curr Protoc Mol Biol. 2010 Jan;Chapter 21:Unit 21.16.1-13
Schübeler, D.

Schleker T, Shimada K, Sack R, Pike BL, Gasser SM Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation Cell Cycle. 2010 Jan 15;9(2):350-63
Gasser, S.

Arany I, Faisal A, Clark JS, Vera T, Baliga R, Nagamine Y p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury Am J Physiol Renal Physiol. 2010 Jan 6. [Epub ahead of print]
Nagamine, Y.

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