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Mar 23, 2018

Breakthrough article on mechanistic features of microRNA targeting and activity

Giovanna Brancati and Helge Grosshans from the FMI have described target specialization of miRNAs of the let-7 family. They identified target site features that determine specificity, and revealed that specificity can be modulated in a manner that allows cells to integrate target site quality and miRNA abundance. Their findings address the unresolved question of how miRNA family members can be targeting different transcripts within the same cell. Read more

Mar 08, 2018

2018 Bressler Prize in Vision Science awarded to Botond Roska

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Jan 18, 2018

Silvia Arber receives 2018 Pradel Research Award

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Dec 18, 2017

Virus stamping - a versatile new method for genetic engineering of single cells

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Next seminars & events

Mar 26, 2018. Time: 13:00  FMI Room 530  Add to my calendar  Register for this event

Transcriptional Repression of Methylated Mammalian Promoters
Matthieu Boulard, EMBL Rome, Epigenetics and Neurobiology Unit, Monterotondo, Italy

Mar 27, 2018. Time: 13:50  FMI Room 530  Add to my calendar  Register for this event

Part of the TriRhena Transcription and Chromatin Club
The HUSH complex: silencing incoming and endogenous retroviruses

Paul Lehner, University of Cambridge, UK
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Mar 27, 2018. Time: 16:20  FMI Room 530  Add to my calendar  Register for this event

Part of the TriRhena Transcription and Chromatin Club
Mechanisms of the Polycomb/trithorax system for maintaining cell identity

Juerg Mueller, Max Planck Institute of Biochemistry, Martinsried, Germany
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Apr 05, 2018. Time: 11:30  FMI Room 530  Add to my calendar  Register for this event

Parsing hippocampal ensembles and acting upon their retrieval
David Dupret, Oxford University, Oxford, UK

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Recent Publications

Ferralli J, Tucker RP, Chiquet-Ehrismann R The teneurin C-terminal domain possesses nuclease activity and is apoptogenic Biol Open. 2018 Mar; 7(3)

Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M, Roignant JY Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d Genes Dev. 2018 Mar; [Epub ahead of print]

de la Mata M, Großhans H Turning the table on miRNAs Nat Struct Mol Biol. 2018 Mar; 25(3):195-197

Fadok JP, Markovic M, Tovote P, Lüthi A New perspectives on central amygdala function Curr Opin Neurobiol. 2018 Mar; 49:141-147

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