Apr 15, 2015

Giant proteins determine properties of neurons

Giant membrane-associated proteins called ankyrins extend into the cytoplasm to arrange and stabilize microtubules in axons and synapses. This determines not only the diameter and hence the functional properties of axons, but also the size, function and stability of synapses. This mechanism underlying the control of neuronal dimensions, functional properties and connectivity was elucidated by Jan Pielage and his group at the Friedrich Miescher Institute for Biomedical Research (FMI). Their findings have been published in Developmental Cell. Read more

Apr 06, 2015

Detailing heterochromatin formation at the onset of life

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Mar 26, 2015

How genes are permanently silenced by small RNAs

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Mar 20, 2015

A spotlight on protein translation

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Next seminars & events

Apr 27, 2015. Time: 11:00  FMI Room 530  Add to my calendar  Register for this event

Exploring biology at the nanoscale with super-resolution microscopy
Melike Lakadamyali, The Institute for Photonic Sciences ICFO, Barcelona, Spain

Apr 29, 2015. Time: 14.00  FMI Room 530  Add to my calendar  Register for this event

A novel light sheet microscope to study mouse pre-implantation development
Petr Strnad, EMBL, Heidelberg, Germany

May 06, 2015. Time: 17.00  FMI Room 530  Add to my calendar  Register for this event

Regulation of motor behavior by basal ganglia circuitry
Anatol Kreitzer, Gladstone Institutes, University of California, San Francisco
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May 11, 2015. Time: 15.00  FMI Room 530  Add to my calendar  Register for this event

Part of the TriRhena Meeting
Epigenetic memory of gene expression

Danesh Moazed, Danesh Moazed, Harvard Medical School, Boston, MA, USA
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Recent Publications

Genoud C, Houades V, Kraftsik R, Welker E, Giaume C Proximity of excitatory synapses and astroglial gap junctions in layer IV of the mouse barrel cortex Neuroscience. 2015 Apr; 291:241-9

Chiovaro F, Martina E, Bottos A, Scherberich A, Hynes NE, Chiquet-Ehrismann R Transcriptional regulation of tenascin-W by TGF-beta signaling in the bone metastatic niche of breast cancer cells Int J Cancer. 2015 Apr; [Epub ahead of print]

Baubec T, Colombo DF, Wirbelauer C, Schmidt J, Burger L, Krebs AR, Akalin A, Schübeler D Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation Nature. 2015 Apr; 520(7546):243-7

Stephan R, Goellner B, Moreno E, Frank CA, Hugenschmidt T, Genoud C1 Aberle H, Pielage J Hierarchical Microtubule Organization Controls Axon Caliber and Transport and Determines Synaptic Structure and Stability Dev Cell. 2015 Apr; 33(1)5-21

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