Jun 24, 2016

Aggressiveness of acute myeloid leukemia elucidated

Antoine Peters and colleagues at the Basel University Children's Hospital (UKBB) have discovered why acute leukemias with the same genetic abnormality vary in their aggressiveness based on their cellular origin. They found that the cancer inducing alteration is particularly devastating if it occurs in early hematopoietic stem cells expressing certain genes involved in cell migration and tissue invasion. These findings should now make it possible to classify patients into more clearly defined groups, to adapt treatment, and hopefully also to develop personalized therapeutic strategies for the future. Read more

Jun 02, 2016

How fear makes us freeze

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May 27, 2016

Double honors for the Bentires-Alj lab

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May 02, 2016

Unraveling complex neuronal networks

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Next seminars & events

Aug 02, 2016. Time: 13.00  FMI Room 530  Add to my calendar  Register for this event

Regulatory Roles of Repeat RNA
John L. Rinn, Harvard Department of Stem Cell & Regenerative Biology, Harvard University, Cambridge, MA, USA

Sep 06, 2016. Time: 12.30  FMI Room 530  Add to my calendar  Register for this event

Basel Breast Consortium Tandem Seminar Series
1. Unravelling mechanisms of breast cancer metastasis
2. Ultrasound in breast cancer diagnostics
3. Translation of genomics into actionable information

1. Curzio Rüegg, Pathology, University of Fribourg
2. Rosanna Zanetti, Claraspital, Basel
3. Matthias Langenfeld, Genomic Health International, Geneva

Sep 30, 2016. Time: 10.15  FMI Room 530  Add to my calendar  Register for this event

Epigenetic mechanisms in early mammalian development
Maria Elena Torres-Padilla, Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum, Munich, Germany

Oct 04, 2016. Time: 16.00  FMI Room 530  Add to my calendar  Register for this event

Title t.b.a.
Tom Cech, University of Colorado, Boulder, CO, USA

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Recent Publications

Wicki A, Mandalà M, Massi D, Taverna D, Tang H, Hemmings BA, Xue G Acquired Resistance to Clinical Cancer Therapy: A Twist in Physiological Signaling Physiol Rev. 2016 Jul; 96(3):805-29

Eymery A, Liu Z, Ozonov EA, Stadler MB, Peters AH The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos Development. 2016 Jun; [Epub ahead of print]

Ferralli J, Chiquet-Ehrismann R, Degen M KLF4a stimulates breast cancer cell proliferation by acting as a KLF4 antagonist. Oncotarget. 2016 Jun; [Epub ahead of print]

Gonzalez-Sandoval A, Gasser SM On TADs and LADs: Spatial Control Over Gene Expression Trends Genet. 2016 Jun; [Epub ahead of print]

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