Oct 16, 2017
Ishan Deshpande and his colleagues from the group of Susan Gasser and the Protein Structure Facility at the FMI elucidated the mechanism of how Mec1-Ddc2, a tumor suppressor involved in DNA damage response assembles at sites of DNA damage. They focus on the Ddc2-RPA interaction, which brings the Mec1-Ddc2 kinase complex to single-stranded DNA at sites of DNA damage. With their structural data, the FMI scientists provide the missing link between two previously published structures, allowing them to assemble a to-scale composite structural model of Mec1-Ddc2 on ssDNA-RPA at DNA damage sites Read more
Sep 14, 2017
Sep 06, 2017
Sep 05, 2017
Oct 24, 2017. Time: 14:00 FMI Room 530 
Cell-type specific signals in the basal forebrain
Balazs Hangya, Hungarian Academy of Sciences, Budapest, Hungary
Oct 25, 2017. Time: 13:00 FMI Room 530
Genetic dissection of the brainstem REM sleep center
Hayashi Yu, International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Japan
Oct 25, 2017. Time: 16:00 FMI Room 530
Hubert Bloch Lecture
Acute myeloid leukemia: learning from mouse models
Jürg Schwaller, Dept. of Biomedicine, University Hospital Basel
Oct 26, 2017. Time: 11.30 FMI Room 530
Shaping the functional structure of the hippocampus
Rosa Cossart, Institut de neurobiology de la méditerranée (Inmed), Marseille, France
Miki TS, Carl SH, Großhans H
Two distinct transcription termination modes dictated by promoters
Genes Dev. 2017 Oct; [Epub ahead of print]
Jeggo PA, Downs JA, Gasser SM
Chromatin modifiers and remodellers in DNA repair and signalling
Philos Trans R Soc Lond B Biol Sci. 2017 Oct; 372(1731)
Poli J, Gasser SM, Papamichos-Chronakis M
The INO80 remodeller in transcription, replication and repair
Philos Trans R Soc Lond B Biol Sci. 2017 Oct; 372(1731)
Habacher C, Ciosk R
ZC3H12A/MCPIP1/Regnase-1-related endonucleases: An evolutionary perspective on molecular mechanisms and biological functions
Bioessays. 2017 Sep; 39(9)
