Jan 29, 2015

Cellular memory of stressful situations

Marc Bühler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have identified a cellular mechanism that buffers stress-induced disruption of heterochromatin and the toxic aggregation of a prion protein. If this mechanism malfunctions, changes in the epigenome remain and are thus "remembered" for many cell divisions, long after the stressful situation resolved. Read more

Jan 06, 2015

Trigger mechanism for recovery after spinal cord injury revealed

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Dec 19, 2014

Two-armed control of ATR, a master regulator of the DNA damage checkpoint

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Dec 11, 2014

FMI scientists secure funding for two projects

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» News archive

Next seminars & events

Feb 03, 2015. Time: 12.15  FMI Room 530  Add to my calendar  Register for this event

Functional genomics, genomics and therapy: Putting one and one together
Roderick Beijersbergen, The Netherlands Cancer Institute, Amsterdam

Feb 10, 2015. Time: 12.15  FMI Room 530  Add to my calendar  Register for this event

PARP inhibitor resistance - what is beyond BRCA1/2 restoration?
Sven Rottenberg, Institute of Animal Pathology, Vetsuisse Faculty, Bern

Feb 12, 2015. Time: 11.30  FMI Room 530  Add to my calendar  Register for this event

Time to decide
Gero Miesenböck, Centre for Neural Circuits and Behavior, University of Oxford, UK

Feb 17, 2015. Time: 12:15  FMI Room 530  Add to my calendar  Register for this event

Clinical relevance of Wnt-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma
Orlando Musso, INSERM, Pontchaillou Hospital, Rennes, France

» More FMI seminars & events

Recent Publications

Baubec T, Colombo DF, Wirbelauer C, Schmidt J, Burger L, Krebs AR, Akalin A, Schübeler D Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation Nature. 2015 Jan; [Epub ahead of print]

Schuebeler, D ESCI award lecture: Regulation, function and biomarker potential of DNA methylation Eur J Clin Invest. 2015 Jan; [Epub ahead of print]

Schübeler D Function and information content of DNA methylation Nature. 2015 Jan; 517(7534):321-6

Zhang L, Tang F, Terracciano L, Hynx D, Kohler R, Bichet S, Hess D, Cron P, Hemmings BA, Hergovich A, Schmitz-Rohmer D NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium Curr Biol. 2015 Jan; [Epub ahead of print]

» More FMI publications

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