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SELECTED PUBLICATIONS
Helge Grosshans


Miki TS, Carl SH, Grosshans H (2017) Two distinct transcription termination modes dictated by promoters.
Genes Dev. [Epub ahead of print]

Aeschimann F, Kumari P, Bartake H, Gaidatzis D, Xu L, Ciosk R, Grosshans H (2017) LIN41 post-transcriptionally silences mRNAs by two distinct and position-dependent mechanisms.
Mol Cell 65:476-489.

Richter H, Katic I, Gut H, Grosshans H (2016) Structural basis and function of XRN2 binding by XTB domains.
Nat Struct Mol Biol 23:164-71

Aeschimann F, Xiong J, Arnold A, Dieterich C, Grosshans H (2015) Transcriptome-wide measurement of ribosomal occupancy by ribosome profiling.
Methods 85:75-89

Rüegger S, Miki TS, Hess D, Grosshans H (2015) The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling.
Nucleic Acids Res 43:3344-57

de la Mata M, Gaidatzis D, Vitanescu M, Stadler MB, Wentzel C, Scheiffele P, Filipowicz W, Grosshans H (2015) Potent degradation of neuronal miRNAs induced by highly complementary targets.
EMBO Rep 16:500-11

Ecsedi M, Rausch M Grosshans H (2015) The let-7 microRNA directs vulval development through a single target.
Dev Cell 32:335-44

Hendriks GJ, Gaidatzis D, Aeschimann F, Grosshans H (2014) Extensive oscillatory gene expression during C. elegans larval development.
Mol Cell 53:380-92.

Katic I, Grosshans H (2013) Targeted heritable mutation and gene conversion by Cas9-CRISPR in Caenorhabditis elegans.
Genetics 195:1173-6

Rüegger S, Grosshans H (2012) MicroRNA turnover: when, how, and why.
Trends Biochem Sci 37:436-46

Chatterjee S, Fasler M, Büssing I, Grosshans H (2011) Target-mediated protection of endogenous microRNAs in C. elegans.
Dev Cell 20:388-396

Büssing I, Yang J-S, Lai EC, Grosshans H (2010) The nuclear export receptor XPO-1 supports primary miRNA processing in C. elegans and Drosophila..
EMBO J 29:1830-1839

Chatterjee S, Grosshans H (2009) Active turnover modulates mature microRNA activity in C. elegans.
Nature 461:546-549

Ding XC, Grosshans H (2009) Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins.
EMBO J 28:213-222

Büssing I, Slack FJ, Grosshans H (2008) let-7 microRNAs in development, stem cells and cancer.
Trends Mol Med 14:400-409

Grosshans H, Filipowicz W (2008) The expanding world of small RNAs.
Nature 451:414-416

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