BIOGRAPHY
LIST OF SELECTED PUBLICATIONS
GROUP MEMBERS
GROUP ALUMNI
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GROUP WEBSITE
SELECTED PUBLICATIONS
Helge Grosshans
Hurschler BA, Harris DT, Grosshans H (2011) The type II poly(A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans.
Nucleic Acids Res. 2011 Mar 16. [Epub ahead of print]
Chatterjee S, Fasler M, Büssing I, Grosshans H (2011) Target-mediated protection of endogenous microRNAs in C. elegans.
Dev Cell 20:388-396
Büssing I, Yang J-S, Lai EC, Grosshans H (2010) The nuclear export receptor XPO-1 supports primary miRNA processing in C. elegans and Drosophila..
EMBO J 29:1830-1839
Grosshans H, Büssing I (2010) MicroRNA biogenesis takes another single hit from microsatellite instability.
Cancer Cell 18:295-7
Chatterjee S, Grosshans H (2009) Active turnover modulates mature microRNA activity in C. elegans.
Nature 461:546-549
Ding XC, Grosshans H (2009) Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins.
EMBO J 28:213-222
Ding XC, Weiler J, Grosshans H (2009) Regulating the regulators: mechanisms controlling the maturation of microRNAs.
Trends Biotechnol 27:27-36
Büssing I, Slack FJ, Grosshans H (2008) let-7 microRNAs in development, stem cells and cancer.
Trends Mol Med 14:400-409
Ding X, Slack FJ, Grosshans H (2008) The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation.
Cell Cycle 7:3083-3090
Grosshans H, Filipowicz W (2008) The expanding world of small RNAs.
Nature 451:414-416
Grosshans H, Johnson T, Reinert KL, Gerstein M, Slack FJ (2005) The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans.
Dev Cell 8:321-330
Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ (2005) RAS is regulated by the let-7 microRNA family.
Cell 120:635-647
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