SELECTED PUBLICATIONS
Nancy E. Hynes

Heinrich C, Keller C, Boulay A, Vecchi M, Bianchi M, Sack R, Lienhard S, Duss S, Hofsteenge J, Hynes NE (2010) Copine-III interacts with ErbB2 and promotes tumor cell migration.
Oncogene [Epub ahead of print]

Boulay A, Breuleux M, Stephan C, Fux C, Brisken C, Fiche M, Stumm M, Lane HA, Hynes NE (2009) The Ret receptor tyrosine kinase functionally interacts with the ER-alpha pathway in breast cancer.
Cancer Res 68: 3743-3751

Fayard B, Bianchi F, Dey J, Moreno E, Djaffer S, Hynes NE*, Monard D* (2009) The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression.
Cancer Res 69:5690-8
*joint senior authors

Hynes NE, Dey JH (2009) PI3K inhibition overcomes trastuzumab resistance: blockade of ErbB2/ErbB3 is not always enough.
Cancer Cell 15:353-355

Hynes NE, MacDonald G (2009) ErbB receptors and signaling pathways in cancer.
Curr Opin Cell Biol 21:177-184

Hynes NE, Stoelzle T (2009) Key signalling nodes in mammary gland development and cancer: Myc.
Breast Cancer Res 11:210

Matsuda Y, Schlange T, Oakeley EJ, Boulay A, Hynes NE (2009) Wnt signaling enhances breast cancer cell motility and blockade of the Wnt pathway by sFRP1 suppresses MDA-MB-231 xenograft growth.
Breast Cancer Res 11:R32

Meira M, Masson R, Stagljar I, Lienhard S, Maurer F, Boulay A, Hynes NE (2009) Memo is a novel cofilin interacting protein that influences PLCg1 and cofilin activities, and is essential for maintaining directionality during ErbB2 induced tumor cell migration.
J Cell Sci 122:787-797

Stoelzle T, Schwarb P, Trumpp A, Hynes NE (2009) c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland.
BMC Biol 7:63

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