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Publications


Jia M, Gut H, Chao JA Structural basis of IMP3 RRM12 recognition of RNA. RNA. 2018 Aug 22
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Kumari P, Aeschimann F, Gaidatzis D, Keusch JJ, Ghosh P, Neagu A, Pachulska-Wieczorek K, Bujnicki JM, Gut H, Großhans H, Ciosk R Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition. Nat Commun. 2018 Apr 19;9(1):1549
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Deshpande I, Seeber A, Shimada K, Keusch JJ, Gut H, Gasser SM Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. Mol Cell. 2017 Oct 19;68(2):431-445.e5
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Seeber A, Hegnauer AM, Hustedt N, Deshpande I, Poli J, Eglinger J, Pasero P, Gut H, Shinohara M, Hopfner KP, Shimada K, Gasser SM RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together. Mol Cell. 2016 Dec 1;64(5):951-966
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Habacher C, Guo Y, Venz R, Kumari P, Neagu A, Gaidatzis D, Harvald EB, Færgeman NJ, Gut H, Ciosk R Ribonuclease-Mediated Control of Body Fat. Dev Cell. 2016 Nov 7;39(3):359-369
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Miyake Y, Keusch JJ, Wang L, Saito M, Hess D, Wang X, Melancon BJ, Helquist P, Gut H, Matthias P Structural insights into HDAC6 tubulin deacetylation and its selective inhibition. Nat Chem Biol. 2016 Sep;12(9):748-54

Richter H, Katic I, Gut H, Großhans H Structural basis and function of XRN2 binding by XTB domains. Nat Struct Mol Biol. 2016 Feb;23(2):164-71

Tocchini C, Keusch JJ, Miller SB, Finger S, Gut H, Stadler MB, Ciosk R The TRIM-NHL protein LIN-41 controls the onset of developmental plasticity in Caenorhabditis elegans. PLoS Genet. 2014 Aug;10(8):e1004533

MacDonald G, Nalvarte I, Smirnova T, Vecchi M, Aceto N, Dolemeyer A, Frei A, Lienhard S, Wyckoff J, Hess D, Seebacher J, Keusch JJ, Gut H, Salaun D, Mazzarol G, Disalvatore D, Bentires-Alj M, Di Fiore PP, Badache A, Hynes NE Memo is a copper-dependent redox protein with an essential role in migration and metastasis. Sci Signal. 2014 Jun 10;7(329):ra56

Shi T, Bunker RD, Mattarocci S, Ribeyre C, Faty M, Gut H, Scrima A, Rass U, Rubin SM, Shore D, Thomä NH Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions. Cell. 2013 Jun 6;153(6):1340-53

Oppikofer M, Kueng S, Keusch JJ, Hassler M, Ladurner AG, Gut H, Gasser SM Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. EMBO J. 2013 Feb 6;32(3):437-49

Chen CI, Keusch JJ, Klein D, Hess D, Hofsteenge J, Gut H Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O-fucosylation. EMBO J. 2012 Jul 18;31(14):3183-97

Zhuravleva E, Gut H, Hynx D, Marcellin D, Bleck CK, Genoud C, Cron P, Keusch JJ, Dummler B, Esposti MD, Hemmings BA Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development. Mol Cell Biol. 2012 Jul;32(14):2685-97

Fischer ES, Scrima A, Böhm K, Matsumoto S, Lingaraju GM, Faty M, Yasuda T, Cavadini S, Wakasugi M, Hanaoka F, Iwai S, Gut H, Sugasawa K, Thomä NH The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation. Cell. 2011 Nov 23;147(5):1024-39

Gut H, Xu G, Taylor GL, Walsh MA Structural basis for Streptococcus pneumoniae NanA inhibition by influenza antivirals zanamivir and oseltamivir carboxylate. J Mol Biol. 2011 Jun 17;409(4):496-503

Schmitges FW, Prusty AB, Faty M, Stützer A, Lingaraju GM, Aiwazian J, Sack R, Hess D, Li L, Zhou S, Bunker RD, Wirth U, Bouwmeester T, Bauer A, Ly-Hartig N, Zhao K, Chan H, Gu J, Gut H, Fischle W, Müller J, Thomä NH Histone methylation by PRC2 is inhibited by active chromatin marks. Mol Cell. 2011 May 6;42(3):330-41

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