We want to understand

the molecular mechanisms

of health and disease

We train and mentor

PhD students

and postdocs

We work on biological

mechanisms that enable

biomedical application

Our 19 research groups

are supported

by cutting-edge

technology platforms

Genome Regulation
Multicellular Systems
Neurobiology

More News

Latest News

Dec 05, 2022

Video: Mighty proteins keep DNA regions close for longer

New work by FMI researchers shows that key proteins help to stabilize the interaction between otherwise highly dynamic DNA structures. The findings shed light onto how the complex folds that help to fit nearly two meters of DNA into the cell’s nucleus influence important biological processes.

Dec 05, 2022

How chemical modifications on DNA keep genes off

Oct 25, 2022

Spotlight on FMIers: Marilyn Vaccaro

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.

330

People

Nationalities

Research Groups

active ERC grants (and equivalent)

Highlights

Why do your PhD at the FMI in Basel, Switzerland

One of the many good reasons to do your PhD at the FMI is our location! Next opening of PhD applications: March 1, 2023

Video: The FMI/Novartis cryo-EM facility

The heads of the joint Novartis-FMI cryo-EM center discuss how the technique is advancing biomedical research and drug discovery.

More Events

Upcoming Seminars & Events

Dec 12, 2022 - 15:00 - Hybrid/FMI 530

Molecular glue degraders: fantastic drugs and where to find them

Thesis Presentation - Zuzanna Kozicka

Dec 14, 2022 - 13:00 - Hybrid/FMI 530

Mechanisms of transcription factor binding and cofactor activity in chromatin

Thesis Presentation - Marco Pregnolato

Dec 16, 2022 - 15:00 - Virtual

Title to be announced

Young Investigator Seminar Series - Nicolas Renier, Paris Brain Institute, Paris, France

More Publications

Latest Publications

Nov 21, 2022

Differential phosphorylation of Clr4(SUV39H) by Cdk1 accompanies a histone H3 methylation switch that is essential for gametogenesis.

Kuzdere T, Flury V, Schalch T, Iesmantavicius V, Hess D, Bühler M

EMBO Rep

Oct 19, 2022

Expression and Crystallization of HDAC6 Tandem Catalytic Domains.

Langousis G, Sanchez J, Kempf G, Matthias P

Methods Mol Biol

Oct 19, 2022

Immunoprecipitation of HDAC6 and Interacting Proteins.

Wang L, Sanchez J, Hess D, Matthias P

Methods Mol Biol

Sep 01, 2022

A high-throughput drug screen reveals means to differentiate triple-negative breast cancer.

Vulin M, Jehanno C, Sethi A, Correia AL, Obradovic MMS, Couto JP, Coissieux MM, Diepenbruck M, Preca BT, Volkmann K, der Maur PA, Schmidt A, Münst S, Sauteur L, Kloc M, Palafox M, Britschgi A, Unterreiner V, Galuba O, Claerr I, Lopez-Romero S, Galli GG, Baeschlin D, Okamoto R, Soysal SD, Mechera R, Weber WP, Radimerski T, Bentires-Alj M

Oncogene

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