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Feb 03, 2017

Transcriptional control of sound discrimination

Filippo Rijli and his team have identified two genes that control sound discrimination in the brain. The Hox2 transcription factors act in the mouse brain stem and ensure that the auditory neurons are precisely connected from the inner ear to higher brain areas. In their absence, mice were still able to hear but no longer able to discern sounds with close, yet distinct, frequencies. Read more

Jan 26, 2017

Switching between freezing and flight

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Jan 24, 2017

Great honor: Silvia Arber awarded Louis-Jeantet Prize for Medicine

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Jan 20, 2017

Cell fate regulation by LIN41: activity determined by binding location

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Next seminars & events

Feb 23, 2017. Time: 11.30  FMI Room 530  Add to my calendar  Register for this event

Single-cell approaches in brain circuit analysis
Csaba Foldy, University of Zurich

Feb 24, 2017. Time: 11.00  FMI Room 530  Add to my calendar  Register for this event

H3K9me is dispensable for C. elegans development but essential for genome integrity
Peter Zeller

Feb 24, 2017. Time: 14.00  FMI Room P.68  Add to my calendar  Register for this event

Approaches to discover treatments for rare monogenic immune disorders
Jana Pachlopnik Schmid, University of Zurich

Feb 28, 2017. Time: 11.00  FMI Room 530  Add to my calendar  Register for this event

Technologies for Genome Science: From single-cell sequencing to massively parallel reporter assays
Georg Seelig, University of Washington, Seattle, WA, USA

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Recent Publications

Hauer MH, Seeber A, Singh V, Thierry R, Sack R, Amitai A, Kryzhanovska M, Eglinger J, Holcman D, Owen-Hughes T, Gasser SM Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates Nat Struct Mol Biol. 2017 Feb; 24(2):99-107

Aeschimann F, Kumari P, Bartake H, Gaidatzis D, Xu L, Ciosk R, Großhans H LIN41 Post-transcriptionally Silences mRNAs by Two Distinct and Position-Dependent Mechanisms Mol Cell. 2017 Feb; 65(3):476-489

Fadok JP, Krabbe S, Markovic M, Courtin J, Xu C, Massi L, Botta P, Bylund K, Müller C, Kovacevic A, Tovote P, Lüthi A A competitive inhibitory circuit for selection of active and passive fear responses Nature. 2017 Feb; 542(7639):96-100

Britschgi A, Duss S, Kim S, Couto JP, Brinkhaus H, Koren S, De Silva D, Mertz KD, Kaup D, Varga Z, Voshol H, Vissieres A, Leroy C, Roloff T, Stadler MB, Scheel CH, Miraglia LJ, Orth AP, Bonamy GM, Reddy VA, Bentires-Alj M The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERa Nature. 2017 Jan; 541(7638):541-545

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