We want to understand

the molecular mechanisms

of health and disease

We train and mentor

PhD students

and postdocs

We work on biological

mechanisms that enable

biomedical application

Our 21 research groups

are supported

by cutting-edge

technology platforms

Epigenetics
Quantitative Biology
Neurobiology

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Latest News

More than just walking: a new role for core brain region

For decades, a key brain area called the mesencephalic locomotor region has been thought to merely regulate locomotion. Now, researchers in Silvia Arber’s group have shown that the region is involved in much more than walking, as it contains distinct populations of neurons that control different body movements. The findings could help to improve certain therapies for Parkinson’s disease, a neurodegenerative condition that leads to tremor, stiffness, and problems controlling different movements.

Homing in on how cells keep gene silencing in check

Researchers identify missing ‘switch’ that controls essential genes

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.

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People

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20

Research Groups

15

active ERC grants

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Upcoming Seminars & Events

Aug 20, 2021 - 15:00

Title to be announced

Young Investigator Seminar Series - Alba Alfonso Garcia, University of California, Davis, CA, USA

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Sep 03, 2021 - 15:00

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Young Investigator Seminar Series - Knaka Rjan, Icahn School of Medicine at Mount Sinai, New York, NY, USA

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More Publications

Latest Publications

The stabilized Pol31-Pol3 interface counteracts Pol32 ablation with differential effects on repair.

Shimada K, Tsai-Pflugfelder M, Vijeh Motlagh ND, Delgoshaie N, Fuchs J, Gut H, Gasser SM

Life Science Alliance

Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture.

Nörpel J, Cavadini S, Schenk AD, Graff-Meyer A, Hess D, Seebacher J, Chao JA, Bhaskar V.

Functional diversity for body actions in the mesencephalic locomotor region.

Ferreira-Pinto MJ, Kanodia H, Falasconi A, Sigrist M, Esposito MS, Arber S.

The BTB-domain transcription factor ZBTB2 recruits chromatin remodelers and a histone chaperone during the exit from pluripotency.

Olivieri D, Paramanathan S, Bardet AF, Hess D, Smallwood SA, Elling U, Betschinger J

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