We want to understand

the molecular mechanisms

of health and disease

We train and mentor

PhD students

and postdocs

We work on biological

mechanisms that enable

biomedical application

Our 23 research groups

are supported

by cutting-edge

technology platforms

Epigenetics
Quantitative Biology
Neurobiology

More News

Latest News

Apr 05, 2020

The circuitous path to adulthood

Genes that time the transition to adulthood are well-studied in the roundworm C. elegans, and at least partially conserved in mammals, where they regulate the onset of puberty. Juvenile worms turn into adults when a protein called LIN-29 accumulates in sufficient amounts. By studying two variants of LIN-29, the group of Helge Grosshans reveals that temporal coordination of events during the transition to adulthood involves a branched pathway rather than a linear chain of events.... Read more

Mar 31, 2020

ERC Advanced Grants for Dirk Schübeler and Nicolas Thomä

Mar 24, 2020

Research group of Andreas Lüthi receives Swiss Brain League Research Prize 2020

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.

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Research Groups

131

Publications in 2019

Highlights

Applications open for our PhD and MD-PhD programs

Learn more about our programs and apply now

New Video - FMI group leader Charisios Tsiairis

What can microscopic aquatic creatures teach us about growing new body parts?

More Events

Upcoming Seminars & Events

Due to the current coronavirus situation, all live seminars and events at the FMI have been cancelled or postponed until further notice.

Apr 16, 2020 - 11:00

Karyopherins regulate nuclear pore complex function

Seminar - Roderick Lim, Biozentrum, University of Basel

Apr 30, 2020 - 13:00

Characterization of a developmental oscillator in C. elegans

Thesis Presentation - Yannick Hauser

Please join his presentation via Zoom. Details will follow soon.

May 04, 2020 - 14:00

Title to be announced

Seminar - Thomas Duchaine, Department of Biochemistry, McGill University, Montreal, Canada

More Publications

Latest Publications

Mar 30, 2020

A branched heterochronic pathway directs juvenile-to-adult transition through two LIN-29 isoforms.

Azzi C, Aeschimann F, Neagu A, Großhans H

Elife

Mar 5, 2020

Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model.

Harr JC, Schmid CD, Muñoz-Jiménez C, Romero-Bueno R, Kalck V, Gonzalez-Sandoval A, Hauer MH, Padeken J, Askjaer P, Mattout A, Gasser SM

Genes Dev

Mar 2, 2020

A virtual reality system to analyze neural activity and behavior in adult zebrafish.

Huang KH, Rupprecht P, Frank T, Kawakami K, Bouwmeester T, Friedrich RW

Nat Methods

Mar 01, 2020

Small RNAs in the Transgenerational Inheritance of Epigenetic Information.

Duempelmann L, Skribbe M, Bühler M

Trends Genet