We want to understand the molecular mechanisms of health and disease
We train and mentor PhD students and postdocs
We work on biological mechanisms that enable biomedical application
Our 20 research groups
are supported by cutting-edge
technology platforms
Genome Regulation
 Multicellular Systems
 Neurobiology
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Latest News

Sep 28, 2026

New tool tracks a hidden protein involved in viral infection and cell cleanup

Ubiquitin is a small protein that usually works by attaching itself to other proteins. But it can also exist freely, on its own or in chains, and this form has been hard to study. FMI researchers and their collaborators have now developed a tool called UBiP10 that can pick out and reveal this free ubiquitin in cells and influenza A virus particles. Using it, they found that free ubiquitin gathers around protein aggregates, offering a new way to study its role in viral infection and the cell’s protein-cleanup systems.

Sep 24, 2026

Mapping how the brain organizes movement
Sep 16, 2026

Former FMI group leader Botond Roska receives world’s largest vision award

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and Novartis Biomedical Research.

330
People
43
Nationalities
20
Research Groups
15
active ERC grants (and equivalent)

Highlights

Applications open for the FMI PhD and MD-PhD Programs

Institute video: Proudly advancing biomedical research and training
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Upcoming Seminars & Events

Oct 19, 2026 - 11:00 - Fab24 0.60/61

Towards reconstituting human embryonic development and organogenesis in vitro

  Seminar - Cantas Alev, Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan

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Oct 20, 2026 - 11:00-12:00 - Fab24 0.60/61

FRIEDRICH MIESCHER LECTURE
Prof. Dr. Antonio Giraldez, Yale

  Friedrich Miescher Lecture - ChromGEM reveals the ultrastructure of active and silent chromatin during genome activation

  » More information

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Oct 29, 2026 - 11:00 - Fab24 0.60/61

Visual Methods in Biology - From exploring data to explaining discoveries

  Seminar - Helena Jambor, University of Applied Sciences of the Grisons, Chur

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More Publications

Latest Publications

Oct 6, 2026

Large transgene arrays cause aberrant transcription and synthetic molting defects.

Katic I, Papasaikas P, Gaidatzis D, Großhans H

G3 (Bethesda)
Sep 25, 2026

A designed ubiquitin-binding protein selectively enriches and visualizes unanchored ubiquitin.

Shi S, Bendel A, Kempf G, Sanchez J, Majima S, Iesmantavicius V, Hess D, Seebacher J, Huang Y, Ghosh S, Cao C, Matthias G, Bode J, Yamauchi Y, Diss G, Matthias P, Wang L

Sci Adv
Sep 23, 2026

Projection-defined modules reveal mouse motor cortex architecture.

Falasconi A, Kanodia H, Lusk N, Yao S, Costa RM, Zeng H, Arber S

Cell
Sep 10, 2026

Representational learning by optimization of neural manifolds in an olfactory memory network.

Hu B, Temiz NZ, Chou CN, Rupprecht P, Meissner-Bernard C, Titze B, Chung S, Friedrich RW

Nat Neurosci

Post of the Week

Congratulations to Devico Haojun Shi, who successfully defended his PhD this week! Devico studied how DNA is packaged in mouse and human sperm, mapping where it remains wrapped around the protein structures that help organize the genome. 🧬🎓

[image or embed]

— FMI science (@fmiscience.bsky.social) September 18, 2026 at 10:56 AM

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