We want to understand

the molecular mechanisms

of health and disease

We train and mentor

PhD students

and postdocs

We work on biological

mechanisms that enable

biomedical application

Our 23 research groups

are supported

by cutting-edge

technology platforms

Epigenetics
Quantitative Biology
Neurobiology

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Latest News

Safeguarding one-way traffic

Animal development is a unidirectional process that steers undifferentiated cells of the early embryo into specialized cell types such as brain, muscle or skin cells. Once differentiated, there is almost no way back. A notable exception is the de-differentiation of mature into immature cell types during injured tissue regeneration. It is unknown if the reversal of cellular specialization proceeds along the same path used by natural development – in reverse direction – or along distinct paths. The Betschinger group has now uncovered ... Read more

Prisca Liberali becomes an EMBO Young Investigator

In remembrance of Max Burger

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.

340

People

45

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23

Research Groups

100+

Publications per Year

Highlights

New Video - FMI group leader Charisios Tsiairis

What can microscopic aquatic creatures teach us about growing new body parts?

150 years of DNA discovery

Did you know that it’s our name giver – Friedrich Miescher – who first discovered DNA/nucleic acid 150 years ago?

National Future Day 2019 at the FMI

See some photos from the event (which took place on November 14, 2019)

More Events

Upcoming Seminars & Events

Dec 12, 2019 - 14:00

Temporal dissection of an enhancer cluster in early embryonic development

Seminar - Christa Bücker, Max Perutz Labs, Vienna

Register for Event Save to Calendar

Dec 13, 2019 - 10:00

Zfp281 orchestrates cell state interconversion

Thesis Presentation - Daniela Mayer

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Dec 13, 2019 - 14:30

Functional dissection of a gene expression oscillator in C. elegans

Thesis Presentation - Milou Meeuse

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More Publications

Latest Publications

Zfp281 orchestrates interconversion of pluripotent states by engaging Ehmt1 and Zic2.

Mayer D, Stadler MB, Rittirsch M, Hess D, Lukonin I, Winzi M, Smith A, Buchholz F, Betschinger J

Surrogate Gradient Learning in Spiking Neural Networks: Bringing the Power of Gradient-based optimization to spiking neural networks

Neftci Emre O, Mostafa Hesham, Zenke Friedemann

IEEE Signal Processing Magazine

Model systems for regeneration: <i>Hydra</i>.

Vogg MC, Galliot B, Tsiairis CD

Adaptive disinhibitory gating by VIP interneurons permits associative learning.

Krabbe S, Paradiso E, d'Aquin S, Bitterman Y, Courtin J, Xu C, Yonehara K, Markovic M, Müller C, Eichlisberger T, Gründemann J, Ferraguti F, Lüthi A

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