We want to understand the molecular mechanisms of health and disease
We train and mentor PhD students and postdocs
We work on biological mechanisms that enable biomedical application
Our 20 research groups
are supported by cutting-edge
technology platforms
Genome Regulation
 Multicellular Systems
 Neurobiology
More News

Latest News

Feb 05, 2026

How a sweet treat can change memories

Memories must be flexible so animals can adapt when the world changes. FMI neuroscientists found that in fruit flies, simply tasting a sugar reward again can weaken all previous associated memories. This process may inspire new ways to safely update harmful or unwanted memories.

Jan 19, 2026

FMI Year in Review 2025
Jan 07, 2026

Announcing recipients of early-career fellowships and grants

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and Novartis Biomedical Research.

330
People
45
Nationalities
19
Research Groups
15
active ERC grants (and equivalent)

Highlights

Video: DNA rhythms orchestrate gene activity across development

Video: Proudly advancing biomedical research and training
More Events

Upcoming Seminars & Events

Mar 03, 2026 - 09:30-12:30 - Fab24 0.60/61

Research Symposium - Group Leader Hiring Structural Biology

  Seminar - schedule will be enclosed soon
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Mar 06, 2026 - 11:00-12:00 - Fab24 0.60/61

Seminar Dr. Oliver Bell
Heterochromatin Gene Silencing in Development and Disease: Insights from Weiss-Kruszka Syndrome and KMT2A-rearranged Leukemia

  Seminar -
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Mar 13, 2026 - 11:00 - Fab24 0.60/61

DNA viruses in focus – From mitochondrial targeting and cell death, to novel research tools

  Young Investigator Seminar Series - Karim Rafie
Groningen Research Institute of Pharmacy, The Netherlands
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More Publications

Latest Publications

Feb 11, 2026

The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2.

Weiss J, Vecchia L, Domjan D, Cavadini S, Sabantsev A, Kempf G, Pathare GR, Brackmann K, Michael AK, Kater L, Hietter-Pfeiffer E, Haddawi M, Kuber UP, Mühlhäusser S, Grand RS, Stadler MB, Deindl S, Thomä NH

Mol Cell
Jan 20, 2026

Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation.

Dahmane S, Schexnaydre E, Zhang J, Singh BK, Rosendal E, Chotiwan N, Sharma KB, Nilsson E, Peters MBA, Yau WL, Rönfeldt S, Lundmark R, Barad BA, Grotjahn DA, Liese S, Carlson A, Överby AK, Carlson LA

Nat Commun
Jan 7, 2026

Prefrontal neural geometry of learned cues guides motivated behaviours.

Winke N, Lüthi A, Herry C, Jercog D

Nature
Jan 01, 2026

Imaging the Cytoplasmic Lives of Single mRNAs.

Misiaszek AD, Chao JA

J Mol Biol

Post of the Week

Thanks to everyone who joined us for our panel discussion to mark the International Day of Women & Girls in Science. We're grateful to our speakers & moderator for an engaging conversation that highlighted the importance of inclusive leadership, diverse perspectives and sustained commitment. #IDWGS

[image or embed]

— FMI science (@fmiscience.bsky.social) February 11, 2026 at 2:26 PM

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