We want to understand

the molecular mechanisms

of health and disease

We train and mentor

PhD students

and postdocs

We work on biological

mechanisms that enable

biomedical application

Our 22 research groups

are supported

by cutting-edge

technology platforms

Epigenetics
Quantitative Biology
Neurobiology

More News

Latest News

Jun 22, 2020

Building corticocerebellar neural circuits

In a comprehensive study, researchers from the Rijli group found that a single Hox transcription factor expressed in a group of neurons of the pontine nucleus - the cerebral cortex most important brainstem relay to the cerebellum - determines the wiring onto these neurons of specific cortical neurons. These findings further our understanding of the molecular logic underlying complex corticocerebellar circuit assembly.

Jun 11, 2020

How transcription factors recognize binding motifs on chromatin

Jun 02, 2020

A genome-scale map of DNA methylation kinetics

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.

340

People

Nationalities

Research Groups

131

Publications in 2019

Highlights

The FMI turns 50 this year

FMI ranks first in success rates for ERC grant applications

Video: FMI group leader Charisios Tsiairis

Upcoming Seminars & Events

Due to the current coronavirus situation, all live seminars and events at the FMI have been cancelled or postponed.
We will feature content in this section once we will have public events again.

More Publications

Latest Publications

Jun 16, 2020

Disease-associated DNA2 nuclease-helicase protects cells from lethal chromosome under-replication.

Falquet B, Ölmezer G, Enkner F, Klein D, Challa K, Appanah R, Gasser SM, Rass U

Nucleic Acids Res

Jun 16, 2020

Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets.

Maheshwari U, Kraus D, Vilain N, Holwerda SJB, Cankovic V, Maiorano NA, Kohler H, Satoh D, Sigrist M, Arber S, Kratochwil CF, Di Meglio T, Ducret S, Rijli FM

Cell Reports

Jun 5, 2020

Restoring light sensitivity using tunable near-infrared sensors.

Nelidova D, Morikawa RK, Cowan CS, Raics Z, Goldblum D, Scholl HPN, Szikra T, Szabo A, Hillier D, Roska B

Science

Jun 2, 2020

A fully automated deep learning pipeline for high-throughput colony segmentation and classification.

Carl SH, Duempelmann L, Shimada Y, Bühler M

Biol Open