We want to understand
the molecular mechanisms
of health and disease
We train and mentor
PhD students
and postdocs
We work on biological
mechanisms that enable
biomedical application
Our 23 research groups
are supported
by cutting-edge
technology platforms
Epigenetics
 Quantitative Biology
 Neurobiology
More News

Latest News

Feb 11, 2020

Connecting two important processes in gene expression

RNA decay plays a fundamental role in gene expression by controlling the quality and quantity of messenger RNAs. However, it has proved difficult to study and is still shrouded in mystery. Scientists from the Bühler group now uncovered key targets, components and functions of mammalian RNA decay pathways, and found that RNA decay is tightly connected to another crucial stage of gene expression: protein synthesis (translation).... Read more

Jan 21, 2020

Reconstructing structure and function of a neuronal circuit
Jan 09, 2020

The Computational Biology platform - Data scientists at the FMI

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.

340
People
43
Nationalities
22
Research Groups
131
Publications in 2019

Highlights

New Video - FMI group leader Charisios Tsiairis

What can microscopic aquatic creatures teach us about growing new body parts?

150 years of DNA discovery

Did you know that it’s our name giver – Friedrich Miescher – who first discovered DNA/nucleic acid 150 years ago?

National Future Day 2019 at the FMI

See some photos from the event

More Events

Upcoming Seminars & Events

Feb 20, 2020 - 11:30

Basel Seminar in Neuroscience (BNSS)
A normative perspective on the diversity of dopamine signals

  Basel Seminars in Neuroscience - Naoshige Uchida, Harvard University, Cambridge, MA, USA
Register for Event Save to Calendar
Feb 21, 2020 - 11:30

Computational Neuroscience Inititative Basel
Reinforcement learning and dopamine

  Seminar - Naoshige Uchida, Harvard University, Cambridge, MA, USA
Register for Event Save to Calendar
Mar 10, 2020 - 13:00

Mini-Symposium on Organoids
***REGISTRATION IS MANDATORY***

  Seminar -
» More information
Register for Event Save to Calendar
More Publications

Latest Publications

Jan 20, 2020

Whitening of odor representations by the wiring diagram of the olfactory bulb.

Wanner AA, Friedrich RW

Nat Neurosci
Jan 15, 2020

Zfp281 orchestrates interconversion of pluripotent states by engaging Ehmt1 and Zic2.

Mayer D, Stadler MB, Rittirsch M, Hess D, Lukonin I, Winzi M, Smith A, Buchholz F, Betschinger J

EMBO J
Jan 14, 2020

Small RNAs in the Transgenerational Inheritance of Epigenetic Information.

Duempelmann L, Skribbe M, Bühler M

Trends Genet
Jan 13, 2020

Chromosome Conformation Capture and Beyond: Toward an Integrative View of Chromosome Structure and Function.

McCord RP, Kaplan N, Giorgetti L

Mol Cell

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