Building face structures by remote control
Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. Now, FMI researchers have identified a DNA region containing multiple regulatory elements that interact with genes across distant chromosomal neighborhoods, ensuring that specific facial structures develop in the right place. The findings may provide new insights into normal head development as well as craniofacial birth defects.
About the FMI
The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.
FMI 2022 Year in Review
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Mighty proteins keep DNA regions close for longer
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Upcoming Seminars & Events
FRIEDRICH MIESCHER LECTURE
The sex and geometry of inter-organ communication
Applications of deep learning in biology
Neurotheory Seminar Series
Signal neutrality, scalar property, and collapsing boundaries: consequences of a learned multi-time scale strategy
Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer.
mutscan-a flexible R package for efficient end-to-end analysis of multiplexed assays of variant effect data.