We want to understand the molecular mechanisms of health and disease
We train and mentor PhD students and postdocs
We work on biological mechanisms that enable biomedical application
Our 23 research groups
are supported by cutting-edge
technology platforms
Genome Regulation
 Multicellular Systems
 Neurobiology
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Latest News

Jun 06, 2023

Building face structures by remote control

Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. Now, FMI researchers have identified a DNA region containing multiple regulatory elements that interact with genes across distant chromosomal neighborhoods, ensuring that specific facial structures develop in the right place. The findings may provide new insights into normal head development as well as craniofacial birth defects.

May 22, 2023

Video: Embryo-like models help map early stages of development
May 02, 2023

Revealing how an embryo’s cells sync up

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.

330
People
40
Nationalities
19
Research Groups
15
active ERC grants (and equivalent)

Highlights

FMI 2022 Year in Review

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Mighty proteins keep DNA regions close for longer

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Upcoming Seminars & Events

Jun 13, 2023 - 14:00 - Hybrid/FMI 530

FRIEDRICH MIESCHER LECTURE
The sex and geometry of inter-organ communication

  Lecture Series - Irene Miguel-Aliaga, MRC London Institute of Medical Sciences, Imperial College London, UK

  » More information

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Jun 14, 2023 - 14:00 - Hybrid/FMI 530

Applications of deep learning in biology

  Thesis Presentation - Bastian Eichenberg
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Jun 16, 2023 - 14:00 - FMI 530

Neurotheory Seminar Series
Signal neutrality, scalar property, and collapsing boundaries: consequences of a learned multi-time scale strategy

  Seminar - Eleni Vasilaki, University of Sheffield, UK
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More Publications

Latest Publications

Jun 01, 2023

Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer.

Couto JP, Vulin M, Jehanno C, Coissieux MM, Hamelin B, Schmidt A, Ivanek R, Sethi A, Bräutigam K, Frei AL, Hager C, Manivannan M, Gómez-Miragaya J, Obradovic MM, Varga Z, Koelzer VH, Mertz KD, Bentires-Alj M

EMBO J
Jun 01, 2023

mutscan-a flexible R package for efficient end-to-end analysis of multiplexed assays of variant effect data.

Soneson C, Bendel AM, Diss G, Stadler MB

Genome Biol
May 29, 2023

Integrative approaches to study enhancer-promoter communication.

Mach P, Giorgetti L

Curr Opin Genet Dev
May 11, 2023

Multimodal characterization of murine gastruloid development.

Suppinger S, Zinner M, Aizarani N, Lukonin I, Ortiz R, Azzi C, Stadler MB, Vianello S, Palla G, Kohler H, Mayran A, Lutolf MP, Liberali P

Cell Stem Cell

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