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Nov 05, 2018

Clues to making drugs for "undruggable" targets

Nicolas Thomä's group at the FMI has joined forces with the group of Benjamin Ebert at Harvard’s Broad Institute to show how thalidomide analogs mediate degradation of many more proteins than previously anticipated. These proteins – zinc finger transcription factors – play a role in cancer and developmental diseases but are difficult drug targets. The new study, published in Science, suggests that thalidomide analogs can be rationally designed to target this challenging class of proteins. Read more

Oct 23, 2018

The epigenetics of cartilage repair and regeneration

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Oct 09, 2018

Retention of the regulatory landscape in mitosis

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Oct 05, 2018

Congratulations to the FMI Prize winners 2018

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» News archive

Next seminars & events

Nov 19, 2018. Time: 13:00  FMI Room 530  Add to my calendar  Register for this event

The role of the testis specific H3 variant H3t in mouse spermatogenesis
Philipp Bammer

Nov 22, 2018. Time: 14:00  FMI Room 530  Add to my calendar  Register for this event

Quantitative principles of branching morphogenesis
Edouard Hannezo, Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria

Nov 22, 2018. Time: 17:15  FMI Room 530  Add to my calendar  Register for this event

Post-transcriptional control of host gene expression during viral infection
Noam Stern-Ginossar, Weizmann Institute of Science, Rehovot, Israel

Nov 23, 2018. Time: 10:15  FMI Room 530  Add to my calendar  Register for this event

Genome Architecture Mapping: discovering chromatin contacts in the mouse brain
Ana Pombo, Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany

» More FMI seminars & events

Recent Publications

da Silveira Dos Santos AX, Liberali P From single cells to tissue self-organization. FEBS J. 2018 Nov 3

Sievers QL, Petzold G, Bunker RD, Renneville A, Slabicki M, Liddicoat BJ, Abdulrahman W, Mikkelsen T, Ebert BL, Thomä NH Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. Science. 2018 Nov 2;362(6414)

Ferreira-Pinto MJ, Ruder L, Capelli P, Arber S Connecting Circuits for Supraspinal Control of Locomotion. Neuron. 2018 Oct 24;100(2):361-374

Keller GB, Mrsic-Flogel TD Predictive Processing: A Canonical Cortical Computation. Neuron. 2018 Oct 24;100(2):424-435

» More FMI publications


Group leaders Videos

Georg Keller (Neurobiology)

Prisca Liberali (Quantitative Biology)
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