We want to understand the molecular mechanisms of health and disease
We train and mentor PhD students and postdocs
We work on biological mechanisms that enable biomedical application
Our 20 research groups
are supported by cutting-edge
technology platforms
Genome Regulation
 Multicellular Systems
 Neurobiology
More News

Latest News

Feb 26, 2025

Charting gene secrets: New insights into genetic switches

Gene regulation underpins nearly every biological process—from cell development to responses to environmental changes, and understanding it can provide insights into cancer and other diseases. Now, FMI researchers have made significant progress in uncovering how transcription factors—proteins that control gene expression—work in fission yeast, a key model organism for studying gene regulation.

Feb 24, 2025

Exploring metabolism and mentorship: A chat with Anupama Hemalatha
Dec 23, 2024

FMI Year in Review 2024

About the FMI

The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and Novartis Biomedical Research.

330
People
45
Nationalities
21
Research Groups
15
active ERC grants (and equivalent)

Highlights

FMI PhD Program - Spring call

Video: Proudly advancing biomedical research and training
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Upcoming Seminars & Events

Mar 20, 2025 - 11:00 - Fab24 0.60/61

Illuminating the regulation of gene expression at the single-molecule level

  Seminar - Sebastian Deindl, Institute for Cell and Molecular Biology, Uppsala, Sweden
Save to Calendar
Mar 20, 2025 - 12:00 - Fab24 0.60/61

Functional implications of excitation-inhibition balance for learning in neural circuits

  Thesis Presentation - Julian Rossbroich
Save to Calendar
Mar 24, 2025 - 10:00 - Fab24 0.60/61

Title tbd.

  Seminar - Fred van Leeuven, Amsterdam University Medical Centers (UMC), Amsterdam, The Netherlands
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More Publications

Latest Publications

Feb 20, 2025

Computational functions of precisely balanced neuronal microcircuits in an olfactory memory network.

Meissner-Bernard C, Jenkins B, Rupprecht P, Bouldoires EA, Zenke F, Friedrich RW, Frank T

Cell Rep
Feb 10, 2025

Multimodal mismatch responses in mouse auditory cortex.

Solyga M, Keller GB

Elife
Jan 13, 2025

Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex.

Meissner-Bernard C, Zenke F, Friedrich RW

Elife
Jan 7, 2025

DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos.

Fanourgakis G, Gaspa-Toneu L, Komarov PA, Papasaikas P, Ozonov EA, Smallwood SA, Peters AHFM

Nat Commun

Post of the Week

Ever wondered if humans experience the same tricky vision-movement mismatches seen in mice? The Keller group is finding out! Today, they've been running EEG & VR experiments in the FMI lobby to explore how our brains handle these conflicts. @georgkeller.bsky.social @solygamagda.bsky.social

[image or embed]

— FMI science (@fmiscience.bsky.social) February 26, 2025 at 3:11 PM

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