Largest study of developmental microRNA dynamics uncovers mechanism of their regulation
Gene expression is controlled by numerous small RNA molecules called microRNAs, or miRNAs. However, specific functions of most miRNAs remain poorly understood. Working in worms, FMI researchers created an encyclopedia of miRNA dynamics during development, uncovering mechanisms of their regulation. The findings help to better understand typical development and may reveal how these tiny molecules contribute to disease when they become dysfunctional.
About the FMI
The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research.
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Neurobiological mechanisms underlying social approach and avoidance behavior
Biozentrum, room U1.101
From Thalidomide to Rational Molecular Glue Design for Targeted Protein Degradation.
HDAC6/aggresome processing pathway importance for inflammasome formation is context dependent.