FMI News Archive
"Mentor matching" helps new PhD students get started during the pandemic
Starting a PhD can be daunting, especially during a pandemic, when uncertainty and social isolation can cause some extra emotional and logistical upheavals. That’s why the FMI launched a ‘mentor matching’ initiative. By pairing senior PhD students with students ...
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‘Tug of war’ between neurons tells the brain when to fear — and when not to be afraid
Fear protects us by making us alert to danger, but the persistence of fearful memories can lead to serious mental conditions. Now, an international team of researchers co-led by Andreas Lüthi has found that the activity of different cells in the brain’s threat-detector...
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Spotlight on FMIers: Gergely Tihanyi
Spotlight on FMIers showcases the lives, work and passions of the institute’s researchers and support staff. This time, graduate student Gergely Tihanyi tells us about his love for food and cooking, and he shares his insights on the FMI Master Chef series — virtual ev...
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In remembrance of Andrew Matus
It is with great sadness that we learned that Andrew Matus passed away on April 26 after a short illness, at the age of 79. Andrew was a group leader at the FMI for nearly 30 years and Titular Professor at the University of Basel. He made pioneering contributions to the field of ...
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ERC Advanced Grant for Silvia Arber
This year’s recipients of the prestigious Advanced Grants from the European Research Council (ERC) have been announced today. The neurobiologist Prof. Silvia Arber, research group leader at the Friedrich Miescher Institute and the Biozentrum of the University of Basel, is a...
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The architect of genome folding
The spatial organization of the genome is fundamental for the regulation of our genes and has to be established de novo during early embryogenesis. By combining powerful Drosophila genetics with 3D chromosome modelling, a collaboration between the Giorgetti group at the ...
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When two worlds meet: a protease that controls small RNA activity
The protection of genome integrity of germ cells is essential for animal fertility. Researchers from the Grosshans group characterized a defense mechanism against selfish genetic elements in the C. elegans germline. They identified a protein processing mechanism that con...
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Congratulations to our fellowship winners
We are pleased to announce the latest FMI winners of prestigious research fellowships, including EMBO, Maria Sklodowska-Curie Actions (MSCA), Human Frontier Science Program (HFSP) and Boehringer Ingelheim Funds (BIF). These grants, targeted at postdocs (and students for BIF), are...
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Spotlight on FMIers: Esther Griesbach
Spotlight on FMIers is a new series that showcases the lives, work and passions of the institute’s researchers and support staff. In the first interview of the series, Esther Griesbach, a postdoctoral fellow in the group of Jeffrey Chao, tells us about herself, the fascinat...
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'Brain state' behind social interaction uncovered
The brain’s emotion-processing center — the amygdala — is one of several brain regions involved in social behavior. But the exact role that this almond-shaped structure plays in the so-called ‘social brain’ remains mysterious. Now, the Lüthi gro...
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New-found molecular signature keeps key genes ready for action
During development, scores of molecular signals prod cells to take on specialized identities and functions. In response to some of these signals, the cellular machinery awakens specific genes called ‘immediate early genes’ within minutes. The Rijli group has now ident...
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Extensive remodeling of chromatin after DNA damage
In eukaryotes, histones are often modified and evicted at site of DNA double-strand breaks in order to facilitate end-resection and break repair. Together with the protein analysis facility of the FMI, the Gasser group has quantified massive changes in the chromatin associated pr...
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Chromatin remodelers never rest to keep our genome open
Chromatin remodelers are needed to take nucleosomes away from DNA in order to make room for transcription factors to bind, and regulate the activity of our genes. It has been unclear how dynamic this process is. Researchers from the Schübeler group now revealed that active r...
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A key regulator for humoral immunity and B lymphoma
The generation of antibodies in B-cells takes place in a dynamic structure that forms during infections, the germinal center (GC). The formation of GCs lays at the heart of the immune response; this process is highly regulated and not fully understood yet. The Matthias group now ...
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Susan Gasser elected director of the ISREC Foundation
FMI Director Emeritus and Group Leader Emeritus, Susan Gasser, has been elected director of the Foundation of the Swiss Institute for Experimental Cancer (ISREC) by the Foundation Council. The ISREC Foundation has contributed to significant discoveries in oncology, and actively a...
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Prisca Liberali awarded prestigious Friedrich Miescher Award
FMI group leader Prisca Liberali, who is also a Professor at the University of Basel, receives the Friedrich Miescher Award 2021 for her research on design principles of tissue organization. The Friedrich Miescher Award is awarded yearly to a young scientist based in Switzerland ...
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Protecting the genome from transposon activation
Transposons are foreign DNA elements capable of random insertion into the genome, an event that can be very dangerous for a cell. Their activity must be silenced to maintain genomic integrity, which is primarily achieved by H3K9me3-mediated repression. Researchers from the Gasser...
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Neuronal circuits for fine motor skills
Writing, driving a screw or throwing darts are only some of the activities that demand a high level of skill. How the brain masters such exquisite movements has now been described in Nature by the group of Silvia Arber. The researchers revealed the existence of a map of brainstem...
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